Click to move or attack. Shift+click to cast a spell with a target. Click the player tile to pass a turn or get an item. Click items in the inventory to use them.
Numpad and arrow keys move*. Numpad 5 to pass a turn or pick up an item. E to explore and descend staircases, F to fight the closest enemy, R to rest, G to get an item off the ground, C to cast the currently selected spell at the nearest creature.
*check if numlock is on if unable to move diagonally